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Liver biopsy from a 5-month old cholestatic infant with ALGS. (A) Hematoxylin and eosin stain of liver biopsy shows a portal tract (arrow) with branches of hepatic artery and portal vein but no bile duct present. (B) Cytokeratin 19 staining highlights minimal ductular reaction around portal tracts (arrow) throughout the biopsy. Scale bar =200 µM. ALGS, Alagille syndrome.
