Table 4.
Detection of megalin and cubilin by mass spectrometry of light chain affinity column eluates.
| Accession | Description | Genes | MW [kDa] | Lambda LC | Kappa LC | ||
|---|---|---|---|---|---|---|---|
| Norm. area | No. Peptides | Norm. area | No. Peptides | ||||
| P98164.3 | Megalin | LRP2 | 521,6 | 7,59E+05 | 21 | 6,03E+05 | 20 |
| O60494.5 | Cubilin | CUBN | 398,5 | 4,13E+05 | 8 | 3,73E+05 | 11 |
Abundance of peptides is calculated as area under the curve (norm. area) of highly specific peptide peaks. Several peptides were identified as specific for megalin and cubilin (no. peptides).