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. 2016 May 2;23(6):275–282. doi: 10.3727/096504016X14562725373798

Figure 4.

Figure 4

Overexpression of miR-146a increased ROS generation and inhibited SOD2 expression. CAOV3 cells were transfected with miR-146a mimics. (A) ROS level was detected by DHE (a superoxide probe, 10 µM) and analyzed by flow cytometry. (B) Relative mRNA expression of miR-146a is shown. (C) Protein expression of miR-146a is shown. CAOV3 cells were transfected with miR-146a inhibitors. (D) Relative mRNA expression of miR-146a is shown. (E) Protein expression of miR-146a is shown. #p < 0.05 indicates statistical significance, compared with scramble.