Figure 1.

IGF-I induced EMT and enhanced the cellular migration ability in NPC cells. CNE2 and Hone1 cells were treated with or without IGF-I (100 ng/ml) for 48 h after being serum starved overnight. (A) Photos were taken at 20× magnification. (B) EMT markers E-cadherin and vimentin were detected by Western blot analysis. (C) Migration ability of CNE2 and Hone1 cells after IGF-I (100 ng/ml) treatment are shown. The indicated values reflect the mean ± standard deviation (SD) from three independent experiments. E-cad, E-cadherin; Vim, vimentin. *IGF-I untreated versus IGF-I treated, p < 0.05.