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. 2016 Jun 7;24(2):109–116. doi: 10.3727/096504016X14611963142254

Figure 4.

Figure 4

miR-34b inactivated Wnt signaling pathway by suppressing HSF1. (A) Western blotting analysis of HSF1 expression in AML cell lines following the HSF1 siRNA introduction. (B, C) Effects of HSF1 silencing on the cell viability of HL-60 and OCI-AML3. (D) AML cell apoptosis before and after treatment with HSF1 siRNA. (E) Western blotting analysis of β-catenin expression in AML cell lines following the transfection of miR-34b mimics or HSF1 siRNA. Each experiment was repeated in triplicate. *p < 0.05 versus control or NC.