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. 2016 Oct 27;24(6):391–398. doi: 10.3727/096504016X14666990347518

Figure 2.

Figure 2

miR-489 mimic transfection suppressed proliferation and invasion of T24 and UMUC3 bladder cancer cell lines. The negative control mimic (NC) or miR-489 mimic was transfected into T24 and UMUC3 human bladder cancer cell lines. After incubation for 48 h, miR-489 expression was detected with real-time qPCR, cell proliferation was detected with the CCK-8 method, and cell invasion was detected with the Transwell invasion assay. (A) miR-489 expression was increased greatly by the miR-489 mimic transfection. (B, C) The miR-489 mimic significantly suppressed the proliferation of T24 and UMUC3 cells. (D) The miR-489 mimic significantly suppressed the invasion of T24 and UMUC3. *p < 0.05, *p < 0.01 versus NC.