Figure 5.
siRNA-PKM2 arrested cell cycle at the G0/G1 phase. (A and B) The percentage of G0/G1 phase cells of SKOV3 was increased, while the percentages of S and G2/M phase cells were decreased in the siRNA-PKM2 treatment group. (C, D) The percentage of G0/G1 phase cells of OVCAR3 was increased, while the percentage of S and G2/M phase cells was decreased in the siRNA-PKM2 treatment group. n = 3, mean ± SD. **p < 0.01, ***p < 0.001 versus Control; ##p < 0.01, ###p < 0.001 versus Negative Control.