Figure 5.

Suppression of USP17 reduced tumorigenesis and progression of NSCLC in vivo. (A) Tumor formation analysis of nude mice (n = 8/group) after 6-week inoculation of indicated H1299 cells with or without USP17 knockdown (1 × 10⁶) through tail vein. Representative lungs are shown (n = 8/group). Data are representative of three independent experiments. (B) Representative hematoxylin and eosin (H&E) staining analysis of each group is shown. (C) The numbers of lung tumor nodules were counted under anatomy microscope. (D) The weight of the lung tumor nodules was analyzed. Data are representative of three independent experiments (mean and SEM).