Table 2.
Univariate OR (95% CI) | p | Multivariate OR (95% CI) | p | |
---|---|---|---|---|
Age at AML relapse (per year) | 0.96 (0.92–0.99) | 0.02 | 0.8 (0.8–0.9) | 0.002 |
Length from AML diagnosis to relapse (per month) | 1.18 (1.075–1.3) | 0.0006 | 1.3 (1.0–1.6) | 0.004 |
Cycles of consolidation therapy prior to relapse (per cycle) | 1.88 (1.03–3.4) | 0.0397 | 1.8 (0.7–4.4) | 0.2 |
Percent blasts at AML relapse | 1.01 (0.997–1.038) | 0.0895 | 1.0 (1.0–1.1) | 0.002 |
Hemoglobin at AML relapse | 1.21 (0.966–1.527) | 0.0966 | 1.7 (1.0–3.1) | 0.04 |
Platelet count at AML relapse | 1.0 (0.99–1.0) | 0.5103 | 1.0 (1.0–1.03) | 0.003 |
Primary versus secondary AML | 2.5 (0.29–21) | 0.39 | ||
WBC at AML relapse | 1.0 (0.98–1.0) | 0.8661 | ||
Cytogenetic risk at AML relapse | ||||
Favorable versus unfavorable | 13 (1.4–133) | 0.02 | ||
Intermediate versus unfavorable | 2.8 (0.5–14) | 0.6 |
OR, odds ratios; with OR >1.0 corresponding to increased odds of the occurrence of CR or CRi; CI, confidence interval.