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miR-16-1 overexpression induced A549 cell apoptosis via regulating the expression of Bcl-2, Bax, and caspase 3. (A, B) miR-16-1 mimics, inhibitors, or control was transfected into A549 cells, and then the expression levels of Bcl-2, Bax, procaspase 3, and cleaved caspase 3 in cells was detected by Western blot. Bcl-2, B-cell CLL/lymphoma 2; Bax, Bcl2-associated X protein. *p < 0.05; **p < 0.01; ***p < 0.001.
