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ARMC8 silencing inhibits the activation of Wnt/β-catenin signaling pathway in OS cells. (A) MG-63 cells were transfected with ARMC8-shRNA or scr-shRNA for 24 h. The protein expression of β-catenin, cyclin D1, and c-Myc was detected by Western blot. (B) Relative expression of β-catenin, cyclin D1, and c-Myc was quantified using Image-Pro Plus 6.0 software after normalization with β-actin. Data represent mean ± SD from three independent experiments. *p < 0.05.
