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HPIP silencing inhibits tumor growth in an allograft murine model. HSC-3 cells (1 × 106 cells/mouse) expressing siRNA-HPIP or negative control were injected subcutaneously into the left flank of nude mice. (A) The tumor volumes were calculated in each group every 1 week from week 1 to week 5. (B) Knockdown of HPIP significantly inhibited tumor weight of BALB/c nude mice. The results are expressed as mean ± SD and n = 3 per group. *p < 0.05 versus mock group.
