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Effects of BMP-7 on TGF-β1-induced FN secretion and apoptosis. NRK-52E cells were treated with TGF-β1 (5 ng/ml), BMP-7 (100 ng/ml), BMP-7 (100 ng/ml) plus TGF-β1 (5 ng/ml) for 8 h. (A) Cell apoptotic rate was identified by flow cytometry. (B) FAS, FASL, and FN expression in cell culture were analyzed using the method of ELISA. Data are expressed as mean ± SD of three independent experiments in triplicate.
