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. 2021 Jan 14;13(2):282. doi: 10.3390/cancers13020282

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Tumor kinetics and survival data from mice treated with 200 μg of IC blocking antibody. Mice were treated every third day for a total of three doses (q3dx3). (A) The tumor growth curves show a decreased tumor growth for anti PD-L1 and anti PD-L1 + anti LAG-3. (B) The Kaplan–Meier curve shows a significant survival benefit for anti PD-L1 and anti PD-L1 + anti LAG-3. Error bars represent the standard deviation, n = 18, pooled data from three independent experiments, * p < 0.05, ** p < 0.01: statistically significant difference in survival.