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. 2021 Jan 27;17(1):e9730. doi: 10.15252/msb.20209730

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© 2021 The Authors. Published under the terms of the CC BY 4.0 license

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure EV3 — A, B
Comparison of over‐representation analysis performed with msigDB HALLMARK pathways between COSMOS networks generated from (A) our patient samples and (B) CPTAC patient cohort. Overall, a very similar set of pathways was significantly over‐represented in both cases, notably PI3K‐AKT‐MTOR signaling, TNFA signaling via NFKB, interferon gamma response, WNT beta catenin signaling, G2M checkpoint and IL6 JAK STAT3 signaling.