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Mechanisms of action of lncRNA-mediated mRNA stability regulation. LncRNAs can modulate mRNA stability through different mechanisms: (A) Direct interaction with miRNA or RBP binding sites in target mRNA; (B) Sequestration of miRNAs or RBPs to avoid their interaction with mRNA molecules; (C) Acting as scaffolds to enhance RBP-mRNA interactions; (D) Interaction with m6A machinery to modulate m6A levels of target mRNAs.
