Figure 1 -.

Bladder biopsy tissue was collected from IC/BPS patients during hydrodistention under anesthesia and stained with H & E. Representative images that highlight some of the definitions set forth in scoring criteria are presented here. Panel a-c illustrates examples of mild, moderate, and severe chronic inflammation. Panel d (at 400X) illustrates the multi-lobulated nuclei of the neutrophils which are present in acute inflammation, as compared to the plasma cells and lymphocytes seen with chronic inflammation (Panel a-c). Panel e represents erosion seen on microscopy as an absence of the superficial layer of cells (solid red arrow) as compared the transitional cells seen on the right side of the image (blue dotted arrow).