Table 4.

Logistic Regression Models Estimating Association between Flu in Second Trimester and Odds of ASD, Stratified by Antibiotic Use during Pregnancy

	Antibiotic use during Pregnancy		No Antibiotic use during Pregnancy
	OR (95% CI)	P-value	OR (95% CI)	P-value
Flu Trim 2 (unadjusted)	1.08 (0.49, 2.35)	0.85	3.81 (1.27 , 11.49)	0.02
Flu Trim 2 (adjusted §)	0.99 (0.43 , 2.28)	0.99	4.05 (1.14 , 14.38)	0.03
Male child	3.37 (2.05 , 5.53)	<0.0001	5.83 (2.14 , 15.86)	<0.001
Child’s year of birth	1.03 (0.96 , 1.12)	0.41	1.11 (0.99 , 1.26)	0.09
Maternal age (years)	1.02 (0.99 , 1.06)	0.19	1.05 (0.98 , 1.12)	0.20
Gestational age (weeks)	0.81 (0.73 , 0.89)	<0.0001	0.93 (0.79 , 1.09)	0.37
C-section delivery	1.08 (0.67 , 1.76)	0.75	1.85 (0.65 , 5.28)	0.25
Low birth weight (<2500 grams)	0.54 (0.25 , 1.15)	0.11	2.46 (0.58 , 10.44)	0.22

^§Adjusted for child sex, child year of birth, maternal age, gestational age, delivery type, and low birthweight.