Table 1.
Scan parameters of 2D CSE-MRI and 3D CSE-MRI in the phantom and animal studies at 3.0T and the preliminary human studies at 1.5T.
| # TE | TEinit/ΔTE (ms) | TR (ms) | FA (°) | FOV (mm3) | ACQ Resolution (mm3) | NOA | ACQ BW (kHz) | PI Acceleration Phase/Slice | Scan Time (minutes) | Temporal Footprint per Slice | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Phantom Study (3.0T) | |||||||||||
| 2D CSE-MRI | 16 | 1.8/1.0 | 18.9 | 9 | 220×220×69+ | 2.3×2.3×2.3+ | 1 | ±100 | 1.5 / 1.0 | 1:34 | 3.1 seconds |
| 2D CSE-MRI high SNR | 16 | 1.8/1.0 | 18.9 | 9 | 220×220×72+ | 2.3×2.3×3.0+ | 4 | ±62.5 | 1.5 / 1.0 | 6:13 | 15.5 seconds |
| 3D CSE-MRI× | 8 | 1.6/1.3 | 12.8 | 9 | 220×220×68 | 1.5×1.5×1.2 | 1* | ±62.5 | 1.5 / 1.0 | 1:40 | 1:40 minutes |
| 3D CSE-MRI high SNR× | 8 | 1.6/1.3 | 12.8 | 9 | 220×220×72 | 1.5×1.7×8.0 | 1* | ±143 | 1.5 / 1.5 | 0:38 | 0:38 minutes |
| Animal Study (3.0T) | |||||||||||
| 2D CSE-MRI | 16 | 1.8/1.0 | 18.7 | 9 | 180×160×140+ | 1.9×1.8×3.0+ | 1 | ±62.5 | 1.5 / 1.0 | 2:11 | 2.8 seconds |
| 3D CSE-MRI | 8 | 1.6/1.3 | 12.9 | 9 | 160×140×140 | 1.1×1.0×2 | 1* | ±62.5 | 1.5 / 1.0 | 4:54⫵ | 4:54 minutes⫵ |
| Human Study (1.5T) | |||||||||||
| 2D CSE-MRI | 12 | 1.5/0.8 | 12.7 | 10 | 420×378×224+ | 2.9×2.9×4.0 | 1 | ±62.5 | 1.5 / 1.0 | 2:14 | 2.4 seconds |
| 3D CSE-MRI | 6 | 1.2/2.0 | 13.9 | 9 | 420×378×228 | 2.2×2.2×3 | 1* | ±83.3 | 2.0 / 1.5 | 1:48⫵ | 1:48 minutes |
| T2 SSFSE | 1 | 100/0 | 4000 | 155 | 380×380×210 | 1.5×1.5×5 | 1 | ±83.3 | 2.0 / 1.0 | 2:40 | 2.8 seconds |
+
Contiguous slices with slice gap=0 mm;
*
3D corner cutting used (20% k-space reduction).
×
No respiratory gating used in phantom study.
⫵
Scan time with respiratory gating. CSE: chemical shift-encoded; FA: flip angle; FOV: field of view; ACQ: acquisition; NOA: number of averages; BW: sampling bandwidth; PI: parallel imaging; SSFSE: single-shot fast spin-echo