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. 2021 Feb 15;12(2):138–148. doi: 10.4239/wjd.v12.i2.138

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Plasma melatonin concentrations in healthy controls and diabetic retinopathy patients. A: Plasma melatonin in the healthy controls, without diabetic retinopathy (NDR), non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) groups; B: The diagnostic effect of plasma melatonin on diabetic retinopathy was discovered using the receiver operating characteristic curve. ^aP < 0.001. NDR: Without diabetic retinopathy; NPDR: Non-proliferative diabetic retinopathy; PDR: Proliferative diabetic retinopathy; DM: Diabetes mellitus; AUC: Area under the receiver operating characteristic curve.