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. 2021 Feb 15;12(2):124–137. doi: 10.4239/wjd.v12.i2.124

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Detection of xCT (the substrate-specific subunit of system Xc^-) and p53 expression in the aorta of db/db mice. A: The localization of xCT was detected by immunofluorescence. xCT is labeled red, and CD31 is labeled green. The nucleus is labeled blue. Scale bar: 100 μm; B and C: The messenger ribonucleic acid levels of p53 and xCT in mice aorta were determined using real-time polymerase chain reaction analyses. β-actin was used for normalization. ^aP < 0.05 vs the control group. ^bP < 0.01 vs the control group.