Table 2.
Results
| Patient 1 | Patient 2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pre-RT (Baseline) | Day 2 | Day 5 | Day 7 | Month 1 | Pre-RT (Baseline) |
Day 2 | Day 5 | Day 7 | Month 1 | |
| Blood test | ||||||||||
| D‑Dimer (mg/dl) | 4.11 | 1.7 | 1.13 | 0.80 | 0.27 | 1 | 0.44 | 0.42 | 0.41 | 0.30 |
| IL‑6 (pg/ml) | 112.2 | 67.1 | 40.1 | 39.8 | 7.76 | 46 | 20 | 12.1 | 6.2 | 4.19 |
| Hb (g/dl) | 15.8 | 15.0 | 15.6 | 15.9 | 15.0 | 12 | 10.7 | 9.9 | 9.9 | 12.9 |
| CRP (mg/dl) | 0.4 | 0.10 | 0.00 | 0.10 | 0.14 | 1 | 0.10 | 0.30 | 0.10 | 0.02 |
| Ferritin (ng/ml) | 747 | 685 | 721 | 775 | 367 | 916 | 647 | 545 | 469 | 185 |
|
Lymphocytes (cells/μl and %) |
760 (8%) |
750 (14%) |
760 (14.4%) |
670 (13.7%) |
1509 (30%) |
740 (27.5%) |
1310 (30.5%) |
760 (22.6%) |
1100 (24.6%) |
700 (6.6%) |
| LDH (UI/l) | 457 | 350 | 341 | 346 | 396 | 727 | 567 | 607 | 523 | 672 |
| Fibrinogen (mg/dl) | 598 | 443 | 458 | 395 | 325 | 492.00 | 516 | 419 | 557 | 260 |
| Radiological assessment (CT scan) | ||||||||||
| CT TSS | 16 | 11 | 9 | 10 | 9 | 7 | ||||
| RUL TSS | 4 | 3 | 3 | 1 | 1 | 1 | ||||
| RML TSS | 3 | 2 | 2 | 1 | 1 | 1 | ||||
| RLL TSS | 3 | 2 | 2 | 3 | 2 | 2 | ||||
| LUL TSS | 3 | 2 | 1 | 2 | 2 | 1 | ||||
| LLL TSS | 3 | 2 | 1 | 3 | 3 | 2 | ||||
| CT subjective | Severe | Moderate | Moderate | Moderate | Moderate | Mild-Moderate | ||||
| Oxygen status | ||||||||||
| Support |
VMK 40% (10L) |
NC 2L |
Part time NC |
None | None | VMK40% (10L) |
VMK 35% (8L) |
VMK 30% (6L) |
Part time NC 2L |
Patient demand (NC 2L) |
| Sp02 | 90% | 94% | 94% | 95% | 95–97% | 91% | 92% | 92% | 94% | 97% |
| Fi02 | 272 | 327 | 350 | 400 | 432 | 268 | 270 | 330 | 337 | 395 |
| COVID-19 status | ||||||||||
| PCR | + | + | + | + | ||||||
RT Radiotherapy; Normal range values: IL‑6 (Interleukin-6) < 7 pg/ml, D‑Dimer < 0.5 mg/l; Hb (Hemoglobin) males 14–18 and females 12–16; CRP (C-Reactive Protein) < 0.500 mg/dl; Ferritin: males 22–322 ng/ml and females 10–291 ng/ml; LDH (Lactate dehydrogenase) 208–378 UI/l, Fibrinogen 200–400 mg/dl, Lymphocytes 45%
CT Computed Tomography, RUL Right upper lobe, RML Right middle lobe, RLL Right lower lobe, LUL Left upper lobe, LLL Left lower lobe, TSS Total Severity Score. 1 = 0–25%; 2 = 26–50%; 3 = 51–75%; 4 = 76–100%, VMK Venturi Mask (Ventimask), NC Nasal Cannula, 02-Sat Oxygen Saturation, PCR Polymerase Chain reaction