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. 2021 Jan 27;196:113927. doi: 10.1016/j.jpba.2021.113927

Table 3.

Stability of VC in plasma and precipitant under various storage conditions (n = 6).

Matrix Storage conditions Time Concentration (mg/L)
Precision Accuracy
Spiked Measured (%) (%)
Plasma Room temperature (RT) 0.75 h 1.5 1.32 3.67 88.17
40 44.13 3.59 110.3
1.5 h 1.5 1.13 6.15 75.17
40 38.9 5.34 97.31
3 h 1.5 1.02 10.04 67.82
40 32.63 6.95 81.6
4°C 2 h 1.5 1.32 8.09 88.1
40 40.53 5.41 101.31
4 h 1.5 1.2 5.85 79.67
40 36.78 6.99 91.92
−40°C 3 d 1.5 1.37 1.92 91.33
40 38.15 2.57 95.36
5 d 1.5 1.49 6.88 99.69
40 41.82 7.62 104.62
8 d 1.5 0.87 4.12 58.23
40 34.77 4.17 86.94
Precipitant RT 2 h 1.5 1.53 4.23 101.93
40 39.12 2.12 97.76
4 h 1.5 1.44 3.46 95.74
40 38.08 2.16 95.23
Long term (-40°C) 3 d 1.5 1.57 2.07 104.95
40 42.85 7.49 107.18
5 d 1.5 1.63 3.81 108.48
40 39.17 2.86 97.9
Autosampler Autosampler (4°C) 24 h 1.5 1.63 4.32 108.48
40 44.47 3.32 111.17
Plasma Three-freeze-thaw cycles 1.5 1.35 3.23 89.91
40 43.15 1.34 107.82