TABLE 3.
Proportion of patients from the NOPHO ITP study and TIKI trial who exhibited complete recovery or chronic ITP during 1‐year follow‐up, according to the Childhood ITP Recovery Score prediction of the chance of recovery at 3‐month follow‐up. The score was split as outlined in the main text
| Low chance of recovery | Intermediate chance of recovery | High chance of recovery | |
|---|---|---|---|
| NOPHO (N = 377) | |||
| N (% of total) | 84 (22%) | 70 (19%) | 223 (59%) |
| Month 3 | 0.37 (0.27‐0.47) | 0.64 (0.53‐0.76) | 0.80 (0.75‐0.85) |
| Month 6 | 0.45 (0.35‐0.56) | 0.73 (0.62‐0.83) | 0.87 (0.82‐0.91) |
| Chronic ITP (old definition) | 0.55 | 0.27 | 0.13 |
| TIKI (N = 194) | |||
| N (% of total) | 28 (14%) | 45 (23%) | 121 (63%) |
| Month 3 | 0.32 (0.15‐0.49) | 0.69 (0.55‐0.82) | 0.85 (0.79‐0.91) |
| Month 6 | 0.46 (0.28‐0.65) | 0.82 (0.71‐0.93) | 0.90 (0.85‐0.95) |
| Chronic ITP (old definition) | 0.54 | 0.18 | 0.10 |
| Month 12 | 0.71 (0.55‐0.88) | 0.87 (0.77‐0.97) | 0.95 (0.91‐0.99) |
| Chronic ITP | 0.29 | 0.13 | 0.05 |
Data are the proportion (95% CI) of patients experiencing a complete recovery at the indicated timepoint. The definition of chronic ITP was changed in 2009 from ITP lasting more than 6 months after the diagnosis to 12 months after the diagnosis. 20
Abbreviations: CI, confidence interval; ITP, immune thrombocytopenia; NOPHO, Nordic Pediatric Hematology‐Oncology ITP study; TIKI, Treatment With or Without Intravenous Immunoglobulins in Kids with ITP trial.