TABLE 2.
Laboratory data of the study population on admission
| ACLF n = 31 | Non‐liver sepsis n = 20 | P value | |
|---|---|---|---|
| Full blood count | |||
| Hemoglobin (g/L) | 84 (66–136) | 93 (79–133) | .02 |
| Plt count (×109/L) | 76 (20–280) | 216 (79–568) | <.0001 |
| WBC count (×109/L) | 11.3 (2.3–25.8) | 13.2 (4.7–22.3) | n.s. |
| Neutrophils (×109/L) | 9.2 (1.3–22.9) | 9.5 (4.0–18.9) | n.s. |
| Lymphocytes (×109/L) | 1.0 (0.3–2.5) | 1.4 (0.5–3.1) | n.s. |
| Monocytes (×109/L) | 0.65 (0.12–2.04) | 0.59 (0.10–1.53) | n.s. |
| Standard coagulation | |||
| INR | 2.0 (1.2–7.7) | 1.2 (1.1–2.2) | <.0001 |
| APTT ratio | 1.6 (1.1–2.4) | 1.2 (1.0–3.4) | <.001 |
| Biochemistry | |||
| Na, mmol/L | 135 (121–149) | 140 (101–152) | .0076 |
| Urea, mmol/L | 10.2 (2.2–18.7) | 8.7 (3.5–22.4) | n.s. |
| Creatinine, µmol/L | 92 (2–329) | 90 (32–365) | n.s. |
| Bilirubin, µmol/L | 164 (10–714) | 7 (2–32) | <.0001 |
| Gamma glutamyl transaminase, IU/L | 76 (15–661) | 64 (13–58) | n.s. |
| Alkaline phosphatase, IU/L | 114 (32–363) | 92 (42–531) | n.s. |
| Aspartate transaminase, IU/L | 80 (13–662) | 64 (13–3718) | n.s. |
| Albumin, g/L | 29 (19–43) | 28 (21–38) | n.s. |
| CRP, mg/L | 35 (2–558) | 216 (23–381) | <.0001 |
| Interleukin 6 (ng/mL) | 77 (35–138) | 60 (41–238) | n.s. |
| Tumor necrosis factor alpha (pg/mL) | 14 (8–53) | 12 (8–444) | n.s. |
| Arterial | |||
| pH | 7.44 (7.33–7.56) | 7.39 (7.27–7.53) | n.s. |
| NH4+, µmol/L | 69 (24–124) | 30 (12–53) | <.0001 |
| Lactate, mmol/L | 1.7 (0.9–4.2) | 1.0 (0.7–1.9) | <.001 |
Shown are medians with ranges.
Abbreviations: APTT, activated partial thromboplastin time; CRP, C‐reactive protein; INR, international normalized ratio; n.s., not significant; plt, platelet; WBC, white blood cell.