FIGURE 2.

The hps4 gene is present only in chromosome 1L, and a 1.9 kb genomic deletion including two exons in the hps4.L gene occurs in the periodic albino mutant. (a) Schematic representation of Xenopus laevis genes in chromosome 1L containing hps4 locus and in chromosome 1S (v9.2, Xenbase). (b) Alignment of DNA sequences between hps4.L region in chromosome 1L and the corresponding position in chromosome 1S. (c) Schematic representation of hps4.L gene in the wild type and in the mutant. Wild‐type hps4.L gene consists of 13 exons interrupted by 12 introns. DNA chromatograms show a 1.9 kb deletion between introns 6 and 8 in the hps4.L gene in the mutant (c, arrowheads). Accession numbers: +/+ hps4.L gene between exons 6 and 9, LC577764 (DDBJ); a^p/a^p hps4.L gene between exons 6 and 9, LC577765 (DDBJ)