FIGURE 3.

Deletion of two exons in the hps4.L gene in the periodic albino mutant leads to a truncated Hps4 protein. Transcripts and inferred amino acid sequences of Hps4.L in the wild type (a) and the mutant (b) are shown. In the wild type, 13 exons of hps4.L gene are transcribed and translated. In contrast, deletion of exons 7 and 8 (b, arrowhead) in hps4.L creates a premature stop codon (b, asterisk) in the mutant, resulting in a truncated Hps4 protein. Mutant Hps4 protein consists of 214 amino acids (b), which is much shorter than the wild‐type Hps4 protein consisting of 683 amino acids (a). Accession numbers: +/+ hps4.L, LC577762 (DDBJ); a^p/a^p hps4.L, LC577763 (DDBJ)