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. 2020 Dec 4;26(72):17574–17580. doi: 10.1002/chem.202003852

Scheme 2.

Scheme 2

a) Proposed masking effect of the pyridinium moiety via a stabilizing ester function by n–π, π–π or n–cation interactions, b) the absence of a side chain on substrate 4 results in the lack of desired product formation.