Table 3.

Longitudinal study of the 14 identified miRNAs with hepatic steatosis and liver fibrosis

miRNA ID	Hepatic Steatosis				Liver Fibrosis
	Beta	SE		P value	Beta	SE	P value
miR‐193a‐5p	0.54		0.16	2.02 × 10−10a	1.11	0.40	5.58 × 10−03b
miR‐4484	0.21		0.10	4.65 × 10−02b	0.41	0.28	1.37 × 10−01
miR‐1306‐5p	−0.33		0.28	2.36 × 10−01	−1.16	−0.73	1.14 × 10−01
miR‐378a‐3p	0.37		0.21	8.19 × 10−02	1.23	0.64	5.67 × 10−02
miR‐6803‐5p	0.13		0.15	3.79 × 10−01	0.70	0.41	8.42 × 10−02
miR‐6870‐3p	−0.22		0.14	1.18 × 10−01	0.07	0.45	8.80 × 10−01
miR‐3937	−0.13		0.09	1.44 × 10−01	−0.18	0.26	4.87 × 10−01
miR‐122‐5p	0.33		0.08	6.06 × 10−05a	0.45	0.18	1.47 × 10−02b
miR‐422a	0.37		0.18	4.12 × 10−02b	0.96	0.54	7.61 × 10−02
miR‐378d	0.54		0.17	1.65 × 10−03a	0.73	0.53	1.69 × 10−01
miR‐187‐3p	−1.01		0.34	2.76 × 10−03a	−0.42	0.98	6.68 × 10−01
miR‐6809‐5p	−0.55		0.24	2.49 × 10−02b	−0.66	−0.76	3.83 × 10−01
miR‐193b‐3p	0.22		0.15	1.42 × 10−01	1.19	0.46	1.02 × 10−02b
miR‐378e	0.50		0.18	7.25 × 10−03b	0.94	0.60	1.14 × 10−01

Model 2: adjusted for age, sex, waist circumference, ever smoking, alcohol consumption, hypertension, diabetes mellitus and serum HDL cholesterol. The table is sorted based on the association of 14 miRNAs with the continues Hounsfield Unit values in the cross‐sectional study. The P values surpassing the Bonferroni‐corrected threshold of P < 3.57 × 10⁻³ (0.05/14 miRNAs) are marked with “a” and nominal associations with P < 0.05 are marked with “b”. Abbreviations: miRNA, microRNA; SE, standard error.