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. 2020 Nov 27;73(1):40–63. doi: 10.1002/iub.2418

FIGURE 3.

FIGURE 3

Structures of bisphosphonates investigated as potential head‐to‐tail prenyl synthase inhibitors. BPH‐608, ‐628, ‐629, and ‐676 for bacterial undecaprenyl diphosphate synthase inhibition; BPH‐364, ‐629, ‐675, and ‐210 for yeast geranylgeranyl diphosphate synthase inhibition; BPH‐210 also good for Trypanosoma brucei farnesyl diphosphate synthase inhibition; BPH‐715 and ‐716 for tumor cell growth inhibition