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Molecular model for 1,25(OH)2D ligand‐dependent activation of VDR‐RXR, specific association of 1,25(OH)2D bound VDR‐RXR with a VDRE in DNA, followed by 1,25(OH)2D‐stimulated transactivation supported by novel comodulators. BAF = BRG1‐associated factors; CTE = C‐terminal extension; HAT = histone acetyl transferase; PBAF = polybromo‐associated BAF; RXR = retinoid X receptor; VDR = vitamin D receptor.
