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(A) Promoter proximal DNA sequence of the mouse Fgf23 gene, and (B) a model for the regulation of mouse FGF23 by 1,25(OH)2D and multiple inputs (hypoferremia, PTH, hyperphosphatemia, hypercalcemia, and low‐energy state) mediated by various transcription factors. HMW= high molecular weight; LMW = low molecular weight; NFAT = nuclear factor of activated T cells; OPN = osteopontin; VDR = vitamin D receptor; VDREs = vitamin D responsive elements.
