TABLE 2.
Baseline characteristics of 44 enrolled COVID‐19 patients as well as clinical symptoms at baseline and days 1, 3, 5, 7, 14, and 30 in the experimental group and the control group
| Baseline characteristics | Condition, layout | Experimental group (N = 26) | Control group (N = 18) | P |
|---|---|---|---|---|
| Degree of disease | Severe, n (%) | 16 (61.50) | 10 (55.60) | |
| Critically ill, n (%) | 10 (38.50) | 8 (44.40) | ||
| Age (Years) | Mean ± SD | 58.31 ± 12.49 | 61.11 ± 11.03 | .447 |
| Median (Minimum, Maximum) | 57.50 (31.00, 83.00) | 64.00 (39.00, 81.00) | ||
| Sex | Male, n (%) | 17 (65.38) | 13 (72.22) | .632 |
| Female, n (%) | 9 (34.62) | 5 (27.78) | ||
| Fever at baseline period | No, n (%) | 13 (50.00) | 10 (55.56) | .717 |
| Yes, n (%) | 13 (50.00) | 8 (44.44) | ||
| Fever at day 1 | No, n (%) | 21 (84.00) | 13 (72.22) | .455# |
| Yes, n (%) | 4 (16.00) | 5 (27.78) | ||
| Fever at days 3 | No, n (%) | 20 (80.00) | 14 (77.78) | 1.000# |
| Yes, n (%) | 5 (20.00) | 4 (22.22) | ||
| Fever at days 5 | No, n (%) | 22 (88.00) | 15 (83.33) | .683# |
| Yes, n (%) | 3 (12.00) | 3 (16.67) | ||
| Fever at days 7 | No, n (%) | 23 (95.83) | 12 (80.00) | .279# |
| Yes, n (%) | 1 (4.17) | 3 (20.00) | ||
| Fever at days 14 | No, n (%) | 20 (95.24) | 12 (85.71) | .551# |
| Yes, n (%) | 1 (4.76) | 2 (14.29) | ||
| Fever at days 30 | No, n (%) | 11 (100.00) | 10 (90.91) | 1.000# |
| Yes, n (%) | 0 (0.00) | 1 (9.09) | ||
| Cough at baseline period | No, n (%) | 10 (38.46) | 8 (44.44) | .691 |
| Yes, n (%) | 16 (61.54) | 10 (55.56) | ||
| Cough at day 1 | No, n (%) | 15 (60.00) | 5 (27.78) | .037* |
| Yes, n (%) | 10 (40.00) | 13(72.22) | ||
| Cough at days 3 | No, n (%) | 18 (72.00) | 8 (44.44) | .068 |
| Yes, n (%) | 7 (28.00) | 10 (55.56) | ||
| Cough at days 5 | No, n (%) | 16(64.00) | 8(44.44) | .203 |
| Yes, n (%) | 9(36.00) | 10(55.56) | ||
| Cough at days 7 | No, n (%) | 20 (83.33) | 11(73.33) | .686# |
| Yes, n (%) | 4 (16.67) | 4 (26.67) | ||
| Cough at days 14 | No, n (%) | 18 (85.71) | 11 (78.57) | .664# |
| Yes, n (%) | 3 (14.29) | 3 (21.43) | ||
| Cough at days 30 | No, n (%) | 9 (81.82) | 9 (81.82) | N/A |
| Yes, n (%) | 2 (18.18) | 2 (18.18) | ||
| Expiratory dyspnea at baseline period | No, n (%) | 18 (69.23) | 10 (55.56) | .354 |
| Yes, n (%) | 8 (30.77) | 8 (44.44) | ||
| Expiratory dyspnea at day 1 | No, n (%) | 20 (80.00) | 8 (44.44) | .016* |
| Yes, n (%) | 5 (20.00) | 10 (55.56) | ||
| Expiratory dyspnea at days 3 | No, n (%) | 21 (84.00) | 10 (55.56) | .040* |
| Yes, n (%) | 4 (16.00) | 8 (44.44) | ||
| Expiratory dyspnea at days 5 | No, n (%) | 22 (88.00) | 10 (55.56) | .031#* |
| Yes, n (%) | 3 (12.00) | 8 (44.44) | ||
| Expiratory dyspnea at days 7 | No, n (%) | 22 (91.67) | 13 (86.67) | .631# |
| Yes, n (%) | 2 (8.33) | 2 (13.33) | ||
| Expiratory dyspnea at days 14 | No, n (%) | 18 (85.71) | 13 (92.86) | .635# |
| Yes, n (%) | 3 (14.29) | 1 (7.14) | ||
| Expiratory dyspnea at days 30 | No, n (%) | 10 (90.91) | 11 (100.00) | 1.000# |
| Yes, n (%) | 1 (9.09) | 0 (0.00) | ||
| Sore throat at baseline period | No, n (%) | 24 (92.31) | 16 (88.89) | 1.000# |
| Yes, n (%) | 2 (7.69) | 2 (11.11) | ||
| Sore throat at day 1 | No, n (%) | 25 (100.00) | 16 (88.89) | .169# |
| Yes, n (%) | 0 (0.00) | 2 (11.11) | ||
| Sore throat at days 3 | No, n (%) | 24 (96.00) | 18 (100.00) | 1.000# |
| Yes, n (%) | 1 (4.00) | 0 (0.00) | ||
| Sore throat at days 5 | No, n (%) | 24 (96.00) | 18 (100.00) | 1.000# |
| Yes, n (%) | 1 (4.00) | 0 (0.00) | ||
| Sore throat at days 7 | No, n (%) | 24 (100.00) | 15 (100.00) | N/A |
| Yes, n (%) | 0 (0.00) | 0 (0.00) | ||
| Sore throat at days 14 | No, n (%) | 21 (100.00) | 14 (100.00) | N/A |
| Yes, n (%) | 0 (0.00) | 0 (0.00) | ||
| Sore throat at days 30 | No, n (%) | 11 (100.00) | 11 (100.00) | N/A |
| Yes, n (%) | 0 (0.00) | 0 (0.00) | ||
| Diarrhea at baseline period | No, n (%) | 25 (96.15) | 14 (77.78) | .142* |
| Yes, n (%) | 1 (3.85) | 4 (22.22) | ||
| Diarrhea at day 1 | No, n (%) | 25 (100.00) | 16 (88.89) | .169* |
| Yes, n (%) | 0 (0.00) | 2 (11.11) | ||
| Diarrhea at days 3 | No, n (%) | 24 (96.00) | 16 (88.89) | .562* |
| Yes, n (%) | 1 (4.00) | 2 (11.11) | ||
| Diarrhea at days 5 | No, n (%) | 23 (92.00) | 16 (88.89) | 1.000* |
| Yes, n (%) | 2 (8.00) | 2 (11.11) | ||
| Diarrhea at days 7 | No, n (%) | 24 (100.00) | 13 (86.67) | .142# |
| Yes, n (%) | 0 (0.00) | 2 (13.33) | ||
| Diarrhea at days 14 | No, n (%) | 21 (100.00) | 14 (100.00) | N/A |
| Yes, n (%) | 0 (0.00) | 0 (0.00) | ||
| Diarrhea at days 30 | No, n (%) | 11 (100.00) | 10 (90.91) | N/A |
| Yes, n (%) | 0 (0.00) | 1 (9.09) | ||
| Chest tightness at baseline period | No, n (%) | 20 (76.92) | 9 (50.00) | .064 |
| Yes, n (%) | 6 (23.08) | 9 (50.00) | ||
| Chest tightness at day 1 | No, n (%) | 21 (84.00) | 13 (72.22) | .455# |
| Yes, n (%) | 4 (16.00) | 5 (27.78) | ||
| Chest tightness at days 3 | No, n (%) | 21(84.00) | 13 (72.22) | .456# |
| Yes, n (%) | 4 (16.00) | 5 (27.78) | ||
| Chest tightness at days 5 | No, n (%) | 21 (84.00) | 15 (83.33) | 1.000# |
| Yes, n (%) | 4 (16.00) | 3 (16.67) | ||
| Chest tightness at days 7 | No, n (%) | 21 (87.50) | 11 (73.33) | .396# |
| Yes, n (%) | 3 (12.50) | 4 (26.67) | ||
| Chest tightness at days 14 | No, n (%) | 16 (76.19) | 13 (92.86) | .366# |
| Yes, n (%) | 5 (23.81) | 1 (7.14) | ||
| Chest tightness at days 30 | No, n (%) | 9 (81.82) | 11 (100.00) | .476# |
| Yes, n (%) | 2 (18.18) | 0 (0.00) |
Note.
*
Represents significant difference in experimental group and control group (P < .05); “n” represents number; “N/A” represents not applicable; “#” represents Fisher's exact test to obtain the P value, and others use χ² test without label.