TABLE 6.
Respiratory function support indicators of 44 COVID‐19 patients in experimental group and control group
| Interview | Indicator | Condition | Experimental group (N = 26) | Control group (N = 18) | P |
|---|---|---|---|---|---|
| Screening period | Noninvasive ventilation therapy | Yes, n (%) | 1 (3.85) | 2 (11.11) | .558 |
| No, n (%) | 25 (96.15) | 16 (88.89) | |||
| Intubation assisted ventilation | Yes, n (%) | 4 (15.38) | 2 (11.11) | 1.000# | |
| No, n (%) | 22 (84.62) | 16 (88.89) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 0 (0.00) | N/A | |
| No, n (%) | 26 (100.00) | 18 (100.00) | |||
| MSCs infusion at day 1 | Noninvasive ventilation therapy | Yes, n (%) | 1 (3.85) | 4 (22.22) | .142# |
| No, n (%) | 25 (96.15) | 14 (77.78) | |||
| Intubation assisted ventilation | Yes, n (%) | 3 (11.54) | 3 (16.67) | .676# | |
| No, n (%) | 23 (88.46) | 15 (83.33) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 0 (0.00) | N/A | |
| No, n (%) | 26 (100.00) | 18 (100.00) | |||
| MSCs infusion at days 3 | Noninvasive ventilation therapy | Yes, n (%) | 1 (3.85) | 2 (11.11) | .558# |
| No, n (%) | 25 (96.15) | 16 (88.89) | |||
| Intubation assisted ventilation | Yes, n (%) | 3 (11.54) | 3 (16.67) | .676# | |
| No, n (%) | 23 (88.46) | 15 (83.33) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 1 (5.56) | .409# | |
| No, n (%) | 26 (100.00) | 17 (94.44) | |||
| MSCs infusion at days 5 | Noninvasive ventilation therapy | Yes, n (%) | 1 (3.85) | 2 (11.11) | .558# |
| No, n (%) | 25 (96.15) | 16 (88.89) | |||
| Intubation assisted ventilation | Yes, n (%) | 4 (15.38) | 3 (16.67) | 1.000# | |
| No, n (%) | 22 (84.62) | 15 (83.33) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 1 (5.56) | .409# | |
| No, n (%) | 26 (100.00) | 17 (94.44) | |||
| MSCs infusion after days 7± 1 | Noninvasive ventilation therapy | Yes, n (%) | 0 (0.00) | 2 (13.33) | .135# |
| No, n (%) | 25 (100.00) | 13 (86.67) | |||
| Intubation assisted ventilation | Yes, n (%) | 4 (16.00) | 4 (26.67) | .444# | |
| No, n (%) | 21 (84.00) | 11 (73.33) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 1 (6.67) | .375# | |
| No, n (%) | 25 (100.00) | 14 (93.33) | |||
| MSCs infusion after days 14± 3 | Noninvasive ventilation therapy | Yes, n (%) | 0 (0.00) | 1 (6.67) | .375# |
| No, n (%) | 25 (100.00) | 14 (93.33) | |||
| Intubation assisted ventilation | Yes, n (%) | 4 (16.00) | 4 (26.67) | .444# | |
| No, n (%) | 21 (84.00) | 11 (73.33) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 1 (4.00) | 0 (0.00) | 1.000# | |
| No, n (%) | 24 (96.00) | 15 (100.00) | |||
| MSCs infusion after days 30 ± 3 | Noninvasive ventilation therapy | Yes, n (%) | 0 (0.00) | 1 (7.69) | .351# |
| No, n (%) | 24 (100.00) | 12 (92.31) | |||
| Intubation assisted ventilation | Yes, n (%) | 2 (8.33) | 4 (30.77) | .157# | |
| No, n (%) | 22 (91.67) | 9 (69.23) | |||
| Extracorporeal membrane oxygenation (ECMO) | Yes, n (%) | 0 (0.00) | 0 (0.00) | N/A | |
| No, n (%) | 24 (100.00) | 13 (100.00) |
Note. “n” represents number; “#” represents Fisher's exact test to obtain the P value, and others use χ² test without label; “N/A” represents not applicable.