TABLE 7.
Inflammatory indices (including CRP and IL‐6) and oxygenation indices (FiO2, SpO2, SaO2, and PaO2) before and after MSCs infusion
| Index (unit) | Before MSCs treatment | After MSCs treatment | P | |
|---|---|---|---|---|
| CRP (mg/L) | N | 65 | 229 | .486 |
| Mean ± SD | 42.27 ± 57.70 | 36.62 ± 52.66 | ||
| Median (Min‐Max) | 13.84 (.41‐200) | 11.18 (.05‐200) | ||
| IL‐6 (pg/mL) | N | 40 | 182 | .375 |
| Mean ± SD | 86.31 ± 250.79 | 352.28 ± 2953.53 | ||
| Median (Min‐Max) | 10.72 (.46‐1436.82) | 13.16 (1.50‐39225.30) | ||
| FiO2 (%) | N | 9 | 14 | .174 |
| Mean ± SD | 58.78 ± 24.28 | 49.57 ± 23.05 | ||
| Median (Min‐Max) | 49.00 (33.00‐102.00) | 40.00 (29.00‐100.00) | ||
| SpO2 (%) | N | 41 | 68 | <.001* |
| Mean ± SD | 94.72 ± 3.40 | 96.04 ± 5.93 | ||
| Median (Min‐Max) | 95.40 (86.00‐99.20) | 98.00 (60.00‐100.00) | ||
| SaO2 (%) | N | 10 | 19 | .068 |
| Mean ± SD | 93.50 ± 3.89 | 90.95 ± 17.70 | ||
| Median (Min‐Max) | 94.00 (84.00‐99.00) | 97.00 (30.00‐100.00) | ||
| PaO2 (mmHg) | N | 44 | 56 | .015* |
| Mean ± SD | 78.89 ± 25.86 | 95.62 ± 39.49 | ||
| Median (Min‐Max) | 70.50 (45.00‐146.00) | 91.25 (24.00‐208.00) |
Note.
*
Represents significant difference (P < .05) by the Wilcoxon rank sum test. “N” represents the number of valid observation data. CRP, C‐reactive protein; FiO2, fraction of inspiration O2; IL‐6, interleukin 6; Min, minimum; Max, maximum; PaO2, partial pressure of oxygen; SaO2, oxygen saturation; .SpO2, peripheral oxygen saturation.