Table 1. Demographic and clinical characteristics on admission of 412 confirmed COVID-19 hospitalized patients at Lyon University Hospitals, France.
| Medical wards (n = 320) | ICU (n = 92) | p-value | |
|---|---|---|---|
| Age(years) | 73 (57–84)* | 68.5 (55.8–78) | 0.03 |
| Age (≥75 years) | 151 (47.2) | 33 (35.9) | 0.06 |
| <50 | 54 (16.9)** | 15 (16.3) | |
| 50–69 | 87 (27.2) | 32 (34.8) | |
| 70–84 | 102 (31.9) | 37 (40.2) | |
| > = 85 | 77 (24.1) | 8 (8.7) | |
| Gender | |||
| Male | 165 (51.6) | 67 (72.8) | 0.0003 |
| Comorbidities | |||
| aCardiovascular disease | 161(50.3) | 35 (38) | 0.04 |
| Systolic arterial pressure (mmHg) | 136 (120–153.2) [292] | 132 (115–147) [85] | 0.15 |
| Diastolic arterial pressure (mmHg) | 78 (67–86) [292] | 77 (62–84) [85] | 0.15 |
| PAS> = 140 and/or PAD> = 90 | 142/292 (48.6) | 36/85 (42.4) | 0.33 |
| Diabetes | 64 (20) | 18 (19.6) | 1 |
| Chronic lung disease | 48 (15) | 14 (15.2) | 1 |
| Renal diseases | 39 (12.2) | 17 (18.5) | 0.12 |
| Malignancy | 42 (13.1) | 13 (14.1) | 0.86 |
| Chronic neurological diseases | 46 (14.4) | 7 (7.6) | 0.11 |
| Liver diseases | 21 (6.6) | 6 (6.5) | 1 |
| Immunodeficiency | 20 (6.2) | 6 (6.5) | 1 |
| Signs and symptoms at admission | |||
| Temperature (°C) | 38 (37–38.4) | 38.3 (37.5–39) | 0.0005 |
| Fever (>37.8°C) | 174 (54.4) | 61 (66.3) | 0.04 |
| Fever (>39.0°C) | 22 (6.9) | 15 (16.3) | 0.01 |
| Historic of fever | 273 (85.3) | 85 (92.4) | 0.08 |
| Cough | 237 (74.1) | 66 (71.7) | 0.69 |
| General weakness | 199 (62.2) | 54 (58.7) | 0.55 |
| Shortness of breath | 141 (44.1) | 71 (77.2) | <0.001 |
| Diffuse pain | 107 (33.4) | 16 (17.4) | 0.003 |
| Diarrhoea | 89 (27.8) | 24 (26.1) | 0.79 |
| Myalgias | 71 (22.2) | 14 (15.2) | 0.19 |
| Headache | 55 (17.2) | 12 (13) | 0.42 |
| Nausea | 43 (13.4) | 11 (12) | 0.86 |
| Runny nose | 40 (12.5) | 9 (9.8) | 0.58 |
| Confusion | 27 (8.4) | 8 (8.7) | 1 |
| Abdominal pain | 31 (9.7) | 2 (2.2) | 0.02 |
| Anosmia | 26/305 (8.5) | 4/92 (4.3) | 0.26 |
| Ageusia | 25/305 (8.2) | 4/92 (4.3) | 0.26 |
| Sore throat | 20 (6.2) | 4 (4.3) | 0.62 |
| Chest pain | 12 (3.8) | 2 (2.2) | 0.74 |
| Joints pain | 7 (2.2) | 1 (1.1) | 0.69 |
| Dyspnoea/tachypnoea | 186 (58.1) | 79 (85.9) | <0.001 |
| Abnormal lung auscultation | 163 (50.9) | 66 (71.7) | 0.0005 |
| Pharyngeal exudate | 21 (6.6) | 6 (6.5) | 1 |
| Oxygen saturation (%) | 95 (92–97) [279] | 88 (82.5–93) [71] | <0.001 |
| Oxygen saturation <90% | 26/279 (9.3) | 38/71 (53.5) | <0.001 |
| Treatment for Covid-19 | 119/304 (39.1) | 70/89 (78.7) | <0.001 |
| Ventilation | 18 (5.6) | 67 (72.8) | <0.001 |
| Duration of symptoms | 15 (12–18.8) [198] | 22.5 (20.2–27) [34] | <0.001 |
| LOS (Alive) | 8 (4–12) [276] | 12.5 (9–17.8) [50] | <0.001 |
| LOS (Deceased | 8.5 (6–13) [44] | 11 (6–18.2) [42] | 0.11 |
| Delays (days) between | |||
| Onset of symptoms and hospital admission | 6 (2–9) | 7 (4–10) | 0.004 |
| < 3 days | 84 (26.2) | 10 (10.9) | |
| 3–10 days | 43 (13.4) | 22 (23.9) | |
| > 10 days | 193 (60.3) | 60 (65.2) | |
| Deceased | 45 (14.1) | 42 (45.7) | <0.001 |
* Median (IQR) for continious variables
** % in paranthese for categorial variables
COVID-19: coronavirus disease 2019; ICU: Intensive care unit; IQR: interquartile range; LOS: length of stay.
P < .05 was considered statistically significant
aCardiovascular disease included hypertension and heart failure
[n] indicates the patients without missing values for continuous variables