Table 3. Determinants associated with admission to intensive care units in 321 Covid-19 patients at Lyon University hospitals, France.

A: With age in the model
	Adjusted OR	95%CI	P-value
Sex
Female  (17/147)	1
Male  (39/174)	1.66	0.76–3.62	0.2
Age (years)
< 70  (27/144)	1
70–85  (21/100)	0.75	0.33–1.7	0.49
85–103  (8/77)	0.17	0.05–0.51	0.002
aTemperature Continuous variable	1.56	1.06–2.28	0.02
Oxygen saturation (%)
90–100  (26/265)	1
<90  (30/56)	12.45	5.27–29.4	<0.0001
Abnormal lung auscultation
No  (13/141)	1
Yes  (43/180)	3.58	1.58–8.11	0.002
C Reactive Protein, mg/L (Normal range <5 mg/L)
≤100  (21/217)	1
>100  (35/104)	2.7	1.29–5.66	0.008
Monocyte count, x109/L (Normal range 0.2–0.9 x109/L)
≥ 0.3  (36/263)	1
< 0.3  (20/58)	3.28	1.40–7.68	0.006
B: With delay between onset and hospital admission in the model
	Adjusted OR	95%CI	P-value
Sex
Female  (17/147)	1
Male  (39/174)	1.88	0.87–4.10	0.11
Delay between onset and hospital admission (day)
0–2  (5/73)	1
3–10  (38/200)	5.96	1.65–21.5	0.006
>10  (13/48)	6.90	1.68–28.4	0.007
aTemperature Continuous variable	1.62	1.10–2.39	0.01
Oxygen saturation (%)
90–100  (26/265)	1
<90  (30/56)	11.48	4.86–27.1	<0.0001
Abnormal lung auscultation
No  (13/141)	1
Yes  (43/180)	3.50	1.56–7.85	0.002
C Reactive Protein, mg/L (Normal range <5 mg/L)
≤100  (21/217)	1
>100  (35/104)	2.01	0.95–4.23	0.07
Monocyte count, x109/L (Normal range 0.2–0.9 x109/L)
≥ 0.3  (36/263)	1
< 0.3  (20/58)	2.86	1.26–6.50	0.02

OR: odds ratio, CI: confdence interval

In multivariable logistic regression: i) ICU admission was the outcome and ii) age or delay between onset and hospital admission sex, continuous temperature, oxygen saturation, abnormal lung auscultation, monocyte count and C-reactive protein were additive covariates, Akaike information criterion = 216.0, test of Hosmer and Lemeshow goodness of fit with 10 bins: P = 0.59

^aodds ratio of ICU admission was multiplied by 1.62 per degree celsius increase