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. 2021 Jan 27;16(1):e0246066. doi: 10.1371/journal.pone.0246066

Fig 5. Inflammatory cytokine expression in myocardial I/R injury with and without glycyrrhizin treatment and levels of cardiac troponin T (cTnT) in plasma.

Fig 5

A. Quantification of tumour necrosis factor-α (TNF-α) expression by RT-PCR comparing myocardial I/R injury with and without glycyrrhizin treatment (the number of animals: n = 5, respectively), ***P < 0.001, comparing myocardial I/R injury with and without glycyrrhizin by one-way analysis of variance (ANOVA) followed by Bonferroni post hoc test B. Quantification of interleukin-1β (IL-1β) expression by RT-PCR comparing myocardial I/R injury with and without glycyrrhizin (the number of animals: n = 5, respectively), ***P < 0.001, comparing myocardial I/R injury with and without glycyrrhizin treatment by one-way ANOVA followed by Bonferroni post hoc test C. Quantification of interleukin-6 (IL-6) expression by RT-PCR comparing myocardial I/R injury with and without glycyrrhizin treatment (the number of animals: n = 5, respectively), ***P < 0.001, comparing myocardial I/R injury with and without glycyrrhizin treatment by one-way ANOVA followed by Bonferroni post hoc test. D. Quantification of serum TnT level by ELISA comparing myocardial I/R with normothermia and hypothermia (33°C and 36°C) (number of animals: n = 5), ***P < 0.001, comparison of myocardial I/R with normothermia and hypothermia (33°C and 36°C) by one-way analysis of variance (ANOVA) followed by Bonferroni post hoc test. E. Quantification of serum TnT level by ELISA with comparing myocardial I/R injury with and without glycyrrhizin pre-treatment (number of animals: n = 5), ***P < 0.001, comparing myocardial I/R injury with and without glycyrrhizin pre-treatment by one-way ANOVA followed by Bonferroni post hoc test.