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. 2020 Jan 9;72(2):222–229. doi: 10.1093/cid/ciaa019

Table 4.

Adjusted Hazard Ratios for the Risk of Symptomatic Norovirus Diarrhea Caused by GII.4 and GII.6, After Prior Infection With 1 of 8 Genotypes, Among 194 Children With Complete Surveillance Data From Birth Until 24 Months of Age

Genotype of Prior Infection Adjusted HR (95% CI) for Symptomatic Infection
GII.4 (n = 92) GII.6 (n = 51)
GI.3 1.43 (.85–2.40) 1.12 (.50–2.51)
GI.5 0.76 (.30–1.89) 0.78 (.27–2.25)
GI.7 1.19 (.68–2.10) 1.45 (.80–2.61)
GII.2 1.32 (.75–2.30) 1.07 (.48–2.40)
GII.4 0.29a (.18–.48) 1.06 (.59–1.90)
GII.6 1.05 (.65–1.66) 0.70 (.38–1.27)
GII.17 0.76 (.40–1.41) 1.21 (.66–2.21)
GII.23 0.72 (.35–1.48) 0.99 (.52–1.88)

HRs include adjustment for length-for-age z score and the duration of exclusive breastfeeding.

Abbreviations: CI, confidence interval; HR, hazard ratio.

aHolds after Holm correction (P < .007).