Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
BTRX-246040 consistently blocks N/OFQ-induced currents. A, Example recording of a N/OFQ (10 nm) responsive neuron where the selective NOP antagonist BTRX-246040 (100 nm) blocked the response to a subsequent N/OFQ application. B, BTRX-246040 blocked N/OFQ responses across VTA neurons, including both TH(+) and TH(–) neurons (n = 6 and 3, respectively; n = 6 no TH data; mean ± SEM in black); **p < 0.01.
