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HTHQ treatment attenuated decreases the concentration of sEng, ET-1, and activin A levels and restored VEGF levels in blood from PE animals. ELISA was used to detect the concentration of sEng (a), VEGF (b), ET-1 (c), and activin A (d) in serum of mice in each group (n = 6). ∗∗P < 0.01 vs. the control group; #P < 0.05 and ##P < 0.01 vs. the PE group.
