Table 1.
Top Significantly Enriched Gene Ontology Terms Among Genes Regulated by TRα
| No. | GO ID | Term | Count | p | FDR |
|---|---|---|---|---|---|
| 1 | GO:6614 | SRP-dependent cotranslational protein targeting to membrane | 45 | <0.001 | <0.001 |
| 2 | GO:19083 | Viral transcription | 47 | <0.001 | <0.001 |
| 3 | GO:6413 | Translational initiation | 51 | <0.001 | <0.001 |
| 4 | GO:184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 45 | <0.001 | <0.001 |
| 5 | GO:6412 | Translation | 60 | <0.001 | <0.001 |
| 6 | GO:6364 | rRNA processing | 53 | <0.001 | <0.001 |
| 7 | GO:51301 | Cell division | 71 | <0.001 | <0.001 |
| 8 | GO:9813 | Flavonoid biosynthetic process | 14 | <0.001 | <0.001 |
| 9 | GO:7067 | Mitotic nuclear division | 54 | <0.001 | <0.001 |
| 10 | GO:30574 | Collagen catabolic process | 24 | <0.001 | <0.001 |
| 11 | GO:7155 | Cell adhesion | 81 | <0.001 | <0.001 |
| 12 | GO:52696 | Flavonoid glucuronidation | 14 | <0.001 | <0.001 |
| 13 | GO:7062 | Sister chromatid cohesion | 30 | <0.001 | <0.001 |
| 14 | GO:2227 | Innate immune response in mucosa | 14 | <0.001 | <0.001 |
| 15 | GO:30198 | Extracellular matrix organization | 41 | <0.001 | <0.001 |
| 16 | GO:30199 | Collagen fibril organization | 16 | <0.001 | <0.001 |
| 17 | GO:52695 | Cellular glucuronidation | 10 | <0.001 | 0.004 |
| 18 | GO:2181 | Cytoplasmic translation | 12 | <0.001 | 0.006 |
| 19 | GO:19731 | Antibacterial humoral response | 15 | <0.001 | 0.028 |
| 20 | GO:19433 | Triglyceride catabolic process | 11 | <0.001 | 0.050 |
FDR, false discovery rate; GO, Gene Ontology.