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. 2021 Jan 12;31(1):128–142. doi: 10.1089/thy.2020.0022

Table 1.

Top Significantly Enriched Gene Ontology Terms Among Genes Regulated by TRα

No. GO ID Term Count p FDR
1 GO:6614 SRP-dependent cotranslational protein targeting to membrane 45 <0.001 <0.001
2 GO:19083 Viral transcription 47 <0.001 <0.001
3 GO:6413 Translational initiation 51 <0.001 <0.001
4 GO:184 Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 45 <0.001 <0.001
5 GO:6412 Translation 60 <0.001 <0.001
6 GO:6364 rRNA processing 53 <0.001 <0.001
7 GO:51301 Cell division 71 <0.001 <0.001
8 GO:9813 Flavonoid biosynthetic process 14 <0.001 <0.001
9 GO:7067 Mitotic nuclear division 54 <0.001 <0.001
10 GO:30574 Collagen catabolic process 24 <0.001 <0.001
11 GO:7155 Cell adhesion 81 <0.001 <0.001
12 GO:52696 Flavonoid glucuronidation 14 <0.001 <0.001
13 GO:7062 Sister chromatid cohesion 30 <0.001 <0.001
14 GO:2227 Innate immune response in mucosa 14 <0.001 <0.001
15 GO:30198 Extracellular matrix organization 41 <0.001 <0.001
16 GO:30199 Collagen fibril organization 16 <0.001 <0.001
17 GO:52695 Cellular glucuronidation 10 <0.001 0.004
18 GO:2181 Cytoplasmic translation 12 <0.001 0.006
19 GO:19731 Antibacterial humoral response 15 <0.001 0.028
20 GO:19433 Triglyceride catabolic process 11 <0.001 0.050

FDR, false discovery rate; GO, Gene Ontology.