Table 2.

Significantly Enriched Kyoto Encyclopedia of Genes and Genomes Pathways Among Genes Regulated by TRα

No.	GO ID	Term	Count	p	Benjamini	FDR
1	hsa03010	Ribosome	50	<0.001	<0.001	<0.001
2	hsa04974	Protein digestion and absorption	32	<0.001	<0.001	<0.001
3	hsa04512	ECM–receptor interaction	28	<0.001	<0.001	<0.001
4	hsa00053	Ascorbate and aldarate metabolism	15	<0.001	<0.001	<0.001
5	hsa00830	Retinol metabolism	23	<0.001	<0.001	<0.001
6	hsa00983	Drug metabolism—other enzymes	19	<0.001	<0.001	<0.001
7	hsa00040	Pentose and glucuronate interconversions	16	<0.001	<0.001	<0.001
8	hsa00860	Porphyrin and chlorophyll metabolism	17	<0.001	<0.001	<0.001
9	hsa00140	Steroid hormone biosynthesis	20	<0.001	<0.001	0.001
10	hsa00980	Metabolism of xenobiotics by cytochrome P450	22	<0.001	<0.001	0.004
11	hsa05204	Chemical carcinogenesis	22	<0.001	<0.001	0.016
12	hsa00982	Drug metabolism—cytochrome P450	19	<0.001	0.001	0.060
13	hsa05322	Systemic lupus erythematosus	29	<0.001	0.001	0.066
14	hsa04510	Focal adhesion	36	<0.001	0.010	0.642
15	hsa04110	Cell cycle	25	<0.001	0.010	0.742
16	hsa04972	Pancreatic secretion	18	0.006	0.103	8.049
17	hsa00790	Folate biosynthesis	6	0.008	0.115	9.490
18	hsa00601	Glycosphingolipid biosynthesis—lacto and neolacto series	8	0.009	0.131	11.441
19	hsa04978	Mineral absorption	11	0.010	0.136	12.522
20	hsa05203	Viral carcinogenesis	31	0.011	0.146	14.051
21	hsa01100	Metabolic pathways	140	0.013	0.154	15.582
22	hsa05146	Amoebiasis	18	0.022	0.246	25.829
23	hsa05222	Small cell lung cancer	15	0.029	0.300	32.598
24	hsa05150	Staphylococcus aureus infection	11	0.030	0.292	32.836
25	hsa04914	Progesterone-mediated oocyte maturation	15	0.035	0.325	37.653
26	hsa00100	Steroid biosynthesis	6	0.036	0.322	38.451
27	hsa04973	Carbohydrate digestion and absorption	9	0.042	0.356	43.555

ECM, extracellular matrix.