Figure 6.

SVD analysis of UV-Vis absorption spectra obtained from iodine-stained insulin fibrils formed by cross-seeding. (A) The diagonal element of the singular matrix. (B) The first (SV1) and second (SV2) columns of the left-singular matrix. (C and D) Transition diagrams obtained by plotting scores of the first (SV1) and second (SV2) rows of the right-singular matrix. Solid lines, each of which represents a two-state transition, were superimposed to show that both of the plots can be described as a multistep transition. To see this figure in color, go online.