Figure 1.

Phase diagrams showing AP behaviors in an uncoupled myocyte under different LQTS conditions. Phase diagrams for AP behaviors under three LQTS conditions (LQT1, LQT2, and LQT3) for seven ventricular AP models are shown. For each panel, the y axis is fold change in P_Ca and the x axis is fold change in G_Kr (LQT1) or G_Ks (LQT2 and LQT3). The white region is normal repolarization, the gray region is RF, and the colored region is the AP exhibiting EADs. The EAD amplitude is indicated by the color scale. (A) LRd model is shown. (B) SB model is shown. (C) HRd model is shown. (D) TP04 model is shown. (E) GB model is shown. (F) ORd model is shown. (G) ToRORd model is shown. To see this figure in color, go online.