Figure 5.

Effects of increasing G_Ks in the short APD region on PVC genesis. 1D cable simulations under the conditions of LQT2 are shown. For all models, α(G_Ks) = 1 and β(G_Ks) ≥ 1. Gray regions are where PVCs occur in the 1D cable. The circled numbers “1,” “2,” and “3” mark different types of responses to the change of α(P_Ca) and β(G_Ks) as discussed in the main text. (A) LRd model is shown. (B) SB model is shown. (C) TP04 model is shown. (D) GB model is shown. (E) ORd model is shown. (F) ToRORd model is shown. To see this figure in color, go online.