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The projection of the first three principal components, PC1, PC2, and PC3, for the (A) GTP-bound and (B) GDP-bound Cdc42. The PCA projection was subject to linkage clustering, and each cluster is shown in a different color. All the systems show three clusters, except the GTP-G12V mutant, which has two. Representatives of the clusters are shown in Fig. S2. To see this figure in color, go online.
