Table 2.
The Averaged Distances (in Angstroms) of Selected Residues from the Pβ Atom of the GDP/GTP Molecule during the Simulation
| System | Thr35-Cα | Gly60-Cα | Ala13-Cα | Tyr32-OH | Gln/Leu61-CD |
|---|---|---|---|---|---|
| Cdc42-GTP | 7.2 ± 0.1 | 6.8 ± 0.3 | 4.0 ± 0.1 | 7.6 ± 1.5 | 9.4 ± 0.8 |
| Cdc42G12V-GTP | 7.2 ± 0.1 | 6.8 ± 0.3 | 4.0 ± 0.1 | 8.1 ± 2.2 | 10.1 ± 0.7 |
| Cdc42Q61L-GTP | 7.3 ± 0.2 | 9.2 ± 1.0 | 4.0 ± 0.1 | 8.0 ± 1.8 | 12.1 ± 1.5 |
| Cdc42-GDP | 6.9 ± 0.3 | 9.5 ± 0.7 | 4.0 ± 0.1 | 13.6 ± 2.9 | 10.5 ± 1.9 |
| Cdc42G12V-GDP | 7.4 ± 0.9 | 9.5 ± 1.8 | 3.9 ± 0.1 | 12.7 ± 2.3 | 10.5 ± 1.8 |
| Cdc42Q61L-GDP | 6.8 ± 0.2 | 9.7 ± 0.5 | 4.0 ± 0.1 | 12.7 ± 2.5 | 12.8 ± 1.5 |