FIGURE 1.
The effect of ABT-263 on hypertrophic scar in vivo. (A) Gross examination of scars after treatment with ABT-263. (B) The thickness of the scar on day 42 after wounding was measured by ultrasound examination and SEI (scar elevation index) was calculated. n = 5. (C) Masson trichrome staining of scars from different groups. Scale bars: 50 μm. (D) The protein expression of collagen I, collagen III, and α-SMA in day 42 wounds, measured by western blotting. n = 5. (E) TUNEL staining and quantification of the percentage of TUNEL-positive cells in day 42 wounds. n = 5. Scale bars: 50 μm. Data represented the means ± SD. ***p < 0.001 vs. control.