Fig. 2. A proposed integrative model for operationalizing pharmacogenomics data sharing and pharmacogenomic cascade testing (PhaCT).

In this model, the ordering of the test, the collection of the patient’s sample, and the translation of genomics data into clinically actionable results will remain the same. However, once the results are finalized, they will be sent to an ancillary patient-managed genomic system (PMGS). Within the PMGS system, patients will have access to the results and will be able to share results with other clinicians or family members. Lastly, the PMGS could also have the ability to send the results to the electronic health record (EHR), which could then be sent to the prescribing physician.